Connecting on World MS Day – May 30th 2021
World MS Day takes place on May 30th every year. The 2021-2022 theme of #Connections underscores the importance of building connections to our communities, to ourselves, and to quality care.
Octave Bioscience proudly partnered with Olink Proteomics for an in-depth technical webinar featuring Ferhan Qureshi, VP of Biomarker Product Development at Octave Bioscience, highlighting the importance of creating connections between organizations shaping MS research.
The current standard of care for MS patients relies heavily on assessments that are subjective, qualitative, and inadequate. Octave Bioscience has developed an integrated care platform that consists of several tools to improve measurement capabilities in MS, including: (1) enhanced MRI readings and interpretation, (2) mobile applications, sensors, and wearables to track shifts and changes in symptoms, and (3) a custom assay panel performed using the Olink platform to quantitatively assess the level of disease activity in blood samples.
To develop this panel, Octave screened over 1000 proteins in several deeply phenotyped studies, then associated those biomarkers with clinical and radiographic endpoints. Octave then used a dynamic and iterative process that balanced statistical, analytical, and biological factors to select proteins for inclusion in the custom panel. The 21-plex panel has been manufactured and analytically validated in preparation for a forthcoming clinical validation in independent cohorts. This informative webinar reviews the research, development, and validation of the custom assay panel.