Our Science

Powerful innovation to transform MS

We're committed to rigorous and ongoing evaluation.

Browse our latest publications below.

Clinical Validation Study Results for a Multivariate Proteomic MS Disease Activity Test

Research Presented at the Annual ACTRIMS Meeting — February 24-26, 2022

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Multivariate Proteomic MS Disease Activity Test Score Performance Evaluated in an Independent Focal Inflammation Cohort

Research Presented at the Annual ACTRIMS Meeting — February 24-26, 2022

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Multivariate Proteomic MS Disease Activity Test Result Distributions Based on Disease Modifying Therapy Categories

Research Presented at the Annual ACTRIMS Meeting — February 24-26, 2022

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Estimation of Disability Status from Blood Serum Protein Concentrations

Research Presented at the Annual ACTRIMS Meeting — February 24-26, 2022

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Analytical Validation of the Disease Activity Score and 4 Disease Pathway Scores for a Multivariate Proteomic Multiple Sclerosis Disease Activity Test

Research Presented at the Annual ACTRIMS Meeting — February 24-26, 2022

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Association Between Serum Biomarkers and Patient-Reported Outcome of Disability in Multiple Sclerosis

Research Presented at the Annual ACTRIMS Meeting — February 24-26, 2022

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Multivariate Proteomic MS Disease Activity Test Results Surfaces Both Individual Patient and Clinical Practice Population Insights

Research Presented at the Annual ACTRIMS Meeting — February 24-26, 2022

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Accounting for Variance in Brain Atrophy Measurements by Quantifying Image Quality Differences across Longitudinal Imaging Studies

Research Presented at the Annual ACTRIMS Meeting — February 24-26, 2022

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Analytical Validation of a Multivariate Proteomic Serum Based Assay for Disease Activity Assessments in Multiple Sclerosis

Research Presented at the Annual ACTRIMS Meeting Virtual Conference — February 25-27, 2021

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Clinical Validation Study Results of a Multivariate Proteomic Serum Based Assay for Disease Activity Assessments in Multiple Sclerosis

Research Presented at the Annual ECTRIMS Meeting Virtual Conference — October 13-15, 2021

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Clinical Validation of a Multivariate Proteomic Serum Based Assay for Disease Activity Assessments in Multiple Sclerosis

Research Presented at the Annual ACTRIMS Meeting Virtual Conference — February 25-27, 2021

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Integrated Analysis of Novel MRI and Blood Serum Biomarkers for the Estimation and Prediction of MS Disease Activity and Progression

Research Presented at the Annual ACTRIMS Meeting Virtual Conference — February 25-27, 2021

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Proteomic Serum Biomarker Signatures Associated with Patient Reported Outcomes in Multiple Sclerosis

Research Presented at the Annual ACTRIMS Meeting Virtual Conference — February 25-27, 2021

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Changes in the Detection of Clinically Relevant White Matter Lesions in MS Using FDA-Cleared Automated Software

Research Presented at the Annual ACTRIMS Meeting Virtual Conference — February 25-27, 2021

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Development of a Custom Multivariate Proteomic Serum Based Assay for Association with Radiographic and Clinical Endpoints in MS

Research Presented at the Joint ACTRIMS-ECTRIMS Meeting MS Virtual 2020 — September 11-13, 2020

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Cross-sectional and longitudinal estimation of radiographic and clinical endpoints to quantify MS disease trajectory with blood serum protein levels.

Research Presented at the Joint ACTRIMS-ECTRIMS Meeting MS Virtual 2020 — September 11-13, 2020

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Improving Patient Outcomes through a Comprehensive Care Management Platform Measuring Outcomes and Value: an Integrated, Novel solution for Generating insights in MS (MOVING MS)

Research Presented at the Joint ACTRIMS-ECTRIMS Meeting MS Virtual 2020 — September 11-13, 2020

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From proteome to interactome: a mechanistic approach to MS biomarker discovery

Research Presented at the Joint ACTRIMS-ECTRIMS Meeting MS Virtual 2020 — September 11-13, 2020

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Improved detection of clinically relevant MRI findings in Multiple Sclerosis radiology reports using FDA-approved quantitative software

Research Presented at the Joint ACTRIMS-ECTRIMS Meeting MS Virtual 2020 — September 11-13, 2020

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BrainGraph: A Novel Visualization of MRI Data as a 3D Graph to Reveal Temporal Features of Disease Progression In Patients with Multiple Sclerosis

Research Presented at the Joint ACTRIMS-ECTRIMS Meeting MS Virtual 2020 — September 11-13, 2020

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High throughput lesion evaluation and quality control for incorporating quantitative imaging metrics into clinical practice

Research Presented at the Joint ACTRIMS-ECTRIMS Meeting MS Virtual 2020 — September 11-13, 2020

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Multivariate protein biomarker models more accurately predict multiple sclerosis MRI disease activity compared to serum levels of neurofilament light chain alone

Research Presented at ECTRIMS 2019 Stockholm, Sweden — September 11-13, 2019

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Classification of high versus low annualized relapse rate status in subjects with relapsing-remitting multiple sclerosis using multivariate serum protein biomarker models

Research Presented at ECTRIMS 2019 Stockholm, Sweden — September 11-13, 2019

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Clinical disease activity status (exacerbation versus quiescence) in subjects with relapsing-remitting multiple sclerosis is accurately classified using multivariate serum protein biomarker models

Research Presented at ECTRIMS 2019 Stockholm, Sweden — September 11-13, 2019

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