Our Science
Powerful innovation to transform MS
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Browse our latest publications below.
Variability in Clinical Decision Making for Neurologists Interpreting MS MRI Brain Reports
Research Presented at the Annual CMSC Meeting - May 31 - June 3
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The Impact of Octave’s Clinical Insights (a patient support program) on Medication Adherence
Research Presented at the Annual CMSC Meeting - May 31 - June 3
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Detection of Silent UTI - a Case Study
Research Presented at the Annual CMSC Meeting - May 31 - June 3
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Variability of Longitudinal Standard of Care Brain MRI Scans Ordered By a Single MS Center
Research Presented at the Annual CMSC Meeting - May 31 - June 3
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Analytical Validation of a Multi-Protein, Serum-Based Assay for Disease Activity Assessments in Multiple Sclerosis
Manuscript Published in Proteomics Clinical Applications
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Disease Modifying Therapy in Newly Diagnosed People with Multiple Sclerosis - A Real-World Administrative Claims Study
Research Presented at the Annual AAN Meeting - April 22-27, 2023
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Real-World Evidence of Tysabri (Natalizumab) Dose Interval Trends in People with Multiple Sclerosis from Administrative Claims Data
Research Presented at the Annual AMCP Meeting - March 21-24, 2023
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Proteomic Biomarker Panel for Gauging Multiple Sclerosis Disease Activity: A Case Series from Real-World Use
Research Presented at the Annual ACTRIMS Meeting - February 23-25, 2023
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Urinary Tract Infections in People with Multiple Sclerosis: A Real-World Administrative Claims Study
Research Presented at the Annual ACTRIMS Meeting - February 23-25, 2023
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Substantial Variability of Neurologist Decision-Making Based on MRI Reports
Research Presented at the Annual ACTRIMS Meeting - February 23-25, 2023
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Blood Serum Proteome Correlates of Multiple Sclerosis Disease Progression as evaluated by Neuropsychological Test Outcomes: A 5-Year Longitudinal Study
Research Presented at the Annual ACTRIMS Meeting - February 23-25, 2023
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Serum Biomarkers of Brain Atrophy in Multiple Sclerosis
Research Presented at the Annual ACTRIMS Meeting - February 23-25, 2023
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Real World Considerations Regarding MRI Use in a Clinic Setting
Research Presented at the Annual ACTRIMS Meeting - February 23-25, 2023
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Sex-Specific Brain Charts for Multiple Sclerosis
Research Presented at the Annual ACTRIMS Meeting - February 23-25, 2023
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Glial Cell Injury and MRI Measures of Chronic Multiple Sclerosis Inflammation
Research Presented at the Annual ACTRIMS Meeting - February 23-25, 2023
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Association between Serum Biomarkers Profile and real world Evidence of Disability in Multiple Sclerosis
Research Presented at the Annual ACTRIMS Meeting - February 23-25, 2023
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Serum Biomarkers of Progression by Proteomic Search in Extreme MS Phenotypes
Research Presented at the Annual ECTRIMS Meeting - October 26-28, 2022
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Investigation of Serum Based Proteomic Biomarker Signatures Relative to Steroid Responsiveness and Disease Activity Status in Relapsing Multiple Sclerosis Patients
Research Presented at the Annual ECTRIMS Meeting - October 26-28, 2022
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Blood Serum Proteome Correlates of Multiple Sclerosis Disease Progression as evaluated by Clinical and Brain Atrophy Outcomes: A 5-Year Longitudinal Study
Research Presented at the Annual ECTRIMS Meeting - October 26-28, 2022
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CMSC 2023 Detection of Silent UTI - A Case Study
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CMSC 2023 Variability of Longitudinal Standard of Care Brain MRI Scans Ordered By a Single MS Center
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CMSC 2023 The Impact of Octave’s Clinical Insights (a patient support program) on Medication Adherence
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CMSC 2023 Variability of Longitudinal Standard of Care Brain MRI Scans Ordered By a Single MS Center
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Longitudinal Testing with a Multivariate Blood Serum Biomarker Panel for Multiple Sclerosis Disease Activity: Patterns of Results in a Real-World Clinical Setting
Research Presented at the Annual ECTRIMS Meeting - October 26-28, 2022
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Clinical Phenotypes from Blood Serum Protein Concentration
Research Presented at the Annual ECTRIMS Meeting - October 26-28, 2022
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Differential Diagnosis Of MS Patients Versus Disease State Controls and Classification of MS Subtypes Using Serum Proteomics
Research Presented at the Annual ECTRIMS Meeting - October 26-28, 2022
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Matched Plasma Modification for Calculating a Disease Activity Score in a Serum-Validated Multivariate Proteomic Multiple Sclerosis Disease Activity Test
Research Presented at the Annual ECTRIMS Meeting - October 26-28, 2022
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Study Design: The Impact of Quantitative Structured MRI Reports on Clinical Decision Making in MS
Research Presented at the Annual ECTRIMS Meeting - October 26-28, 2022
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Multiple Sclerosis MRI Reports Vary Among Neuroradiologists
Research Presented at the Annual ECTRIMS Meeting - October 26-28, 2022
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Tracking Longitudinal Change in Brain Volumes through Conditional Quantiles
Research Presented at the Annual ECTRIMS Meeting - October 26-28, 2022
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Brain Charts for People Living with Multiple Sclerosis
Research Presented at the Annual ECTRIMS Meeting - October 26-28, 2022
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Multivariate Proteomic Analysis and the Relationship with Axonal Pathology in Multiple Sclerosis: A Longitudinal 5-Year Diffusion Tensor Imaging Study
Research Presented at the Annual ECTRIMS Meeting - October 26-28, 2022
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Multivariate Proteomic MS Disease Activity Test Results Surfaces Both Individual Patient and Clinical Practice Population Insights
Research Presented at the Annual CMSC Meeting — June 1-4, 2022
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Clinical Validation Study Results for a Multivariate Proteomic MS Disease Activity Test
Research Presented at the Annual ACTRIMS Meeting — February 24-26, 2022
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Multivariate Proteomic MS Disease Activity Test Score Performance Evaluated in an Independent Focal Inflammation Cohort
Research Presented at the Annual ACTRIMS Meeting — February 24-26, 2022
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Multivariate Proteomic MS Disease Activity Test Result Distributions Based on Disease Modifying Therapy Categories
Research Presented at the Annual ACTRIMS Meeting — February 24-26, 2022
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Estimation of Disability Status from Blood Serum Protein Concentrations
Research Presented at the Annual ACTRIMS Meeting — February 24-26, 2022
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Analytical Validation of the Disease Activity Score and 4 Disease Pathway Scores for a Multivariate Proteomic Multiple Sclerosis Disease Activity Test
Research Presented at the Annual ACTRIMS Meeting — February 24-26, 2022
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Association Between Serum Biomarkers and Patient-Reported Outcome of Disability in Multiple Sclerosis
Research Presented at the Annual ACTRIMS Meeting — February 24-26, 2022
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Multivariate Proteomic MS Disease Activity Test Results Surfaces Both Individual Patient and Clinical Practice Population Insights
Research Presented at the Annual ACTRIMS Meeting — February 24-26, 2022
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Accounting for Variance in Brain Atrophy Measurements by Quantifying Image Quality Differences across Longitudinal Imaging Studies
Research Presented at the Annual ACTRIMS Meeting — February 24-26, 2022
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Analytical Validation of a Multivariate Proteomic Serum Based Assay for Disease Activity Assessments in Multiple Sclerosis
Research Presented at the Annual ACTRIMS Meeting Virtual Conference — February 25-27, 2021
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Clinical Validation Study Results of a Multivariate Proteomic Serum Based Assay for Disease Activity Assessments in Multiple Sclerosis
Research Presented at the Annual ECTRIMS Meeting Virtual Conference — October 13-15, 2021
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Clinical Validation of a Multivariate Proteomic Serum Based Assay for Disease Activity Assessments in Multiple Sclerosis
Research Presented at the Annual ACTRIMS Meeting Virtual Conference — February 25-27, 2021
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Integrated Analysis of Novel MRI and Blood Serum Biomarkers for the Estimation and Prediction of MS Disease Activity and Progression
Research Presented at the Annual ACTRIMS Meeting Virtual Conference — February 25-27, 2021
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Proteomic Serum Biomarker Signatures Associated with Patient Reported Outcomes in Multiple Sclerosis
Research Presented at the Annual ACTRIMS Meeting Virtual Conference — February 25-27, 2021
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Changes in the Detection of Clinically Relevant White Matter Lesions in MS Using FDA-Cleared Automated Software
Research Presented at the Annual ACTRIMS Meeting Virtual Conference — February 25-27, 2021
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Development of a Custom Multivariate Proteomic Serum Based Assay for Association with Radiographic and Clinical Endpoints in MS
Research Presented at the Joint ACTRIMS-ECTRIMS Meeting MS Virtual 2020 — September 11-13, 2020
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Cross-sectional and longitudinal estimation of radiographic and clinical endpoints to quantify MS disease trajectory with blood serum protein levels.
Research Presented at the Joint ACTRIMS-ECTRIMS Meeting MS Virtual 2020 — September 11-13, 2020
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Improving Patient Outcomes through a Comprehensive Care Management Platform Measuring Outcomes and Value: an Integrated, Novel solution for Generating insights in MS (MOVING MS)
Research Presented at the Joint ACTRIMS-ECTRIMS Meeting MS Virtual 2020 — September 11-13, 2020
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From proteome to interactome: a mechanistic approach to MS biomarker discovery
Research Presented at the Joint ACTRIMS-ECTRIMS Meeting MS Virtual 2020 — September 11-13, 2020
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Improved detection of clinically relevant MRI findings in Multiple Sclerosis radiology reports using FDA-approved quantitative software
Research Presented at the Joint ACTRIMS-ECTRIMS Meeting MS Virtual 2020 — September 11-13, 2020
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BrainGraph: A Novel Visualization of MRI Data as a 3D Graph to Reveal Temporal Features of Disease Progression In Patients with Multiple Sclerosis
Research Presented at the Joint ACTRIMS-ECTRIMS Meeting MS Virtual 2020 — September 11-13, 2020
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High throughput lesion evaluation and quality control for incorporating quantitative imaging metrics into clinical practice
Research Presented at the Joint ACTRIMS-ECTRIMS Meeting MS Virtual 2020 — September 11-13, 2020
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Multivariate protein biomarker models more accurately predict multiple sclerosis MRI disease activity compared to serum levels of neurofilament light chain alone
Research Presented at ECTRIMS 2019 Stockholm, Sweden — September 11-13, 2019
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Classification of high versus low annualized relapse rate status in subjects with relapsing-remitting multiple sclerosis using multivariate serum protein biomarker models
Research Presented at ECTRIMS 2019 Stockholm, Sweden — September 11-13, 2019
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Clinical disease activity status (exacerbation versus quiescence) in subjects with relapsing-remitting multiple sclerosis is accurately classified using multivariate serum protein biomarker models
Research Presented at ECTRIMS 2019 Stockholm, Sweden — September 11-13, 2019
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